BloG
Here finds you the updates from our reporter Dolly.
5 reasons why ribonucleoproteins are a better alternative to CRISPR plasmids
Dr. Brittany Enzmann from Synthego has recently published an article discussing about why ribonucleoprotein (RNP) is a better alternative to CRISPR plasmids for CRISPR genome editing experiments. Below are highlights from the article:1. RNPs Reduce the Total...
How CRISPR editing is advancing cancer cell line research
Dr. Rebecca Roberts from Synthego has recently published an article discussing applications of CRISPR in cancer cell lines and how CRISPR editing is advancing cancer cell line research. The advent of CRISPR genome engineering technology has enabled many breakthroughs...
![[Webinar] Illumina – Mission Bio on novel somatic mutations](https://mloqfv3z7rvn.i.optimole.com/qJ5Rjo4-WgFpg3QH/w:400/h:250/q:auto/rt:fill/g:ce/https://lab-a-porter.com/wp-content/uploads/2021/07/20210721_banner11-1.jpg)
[Webinar] Illumina – Mission Bio on novel somatic mutations
Webinar: Multiple Somatic Mutations Synergize to Drive Cerebral Cavernous Malformations In this webinar, Daniel Snellings from the Duke University Medical Centre shares the role of somatic mutations in the pathogenesis of vascular malformations with specific...
Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells
OverviewScience Advances has recently published a research article discussing how the PDL1-PD1 immune checkpoint inhibits T cell activation. Checkpoint immunotherapy is known to be a revolutionizing treatment for previously refractive tumors. However, researchers had...
Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
Overview Signal Transduction and Targeted Therapy has recently published a review article that reported the current expertise about how SARS-CoV-2 attaches on the surface of host cells through a variety of receptors, such as ACE2, neuropilin-1, AXL, and antibody-FcyR...
The mini lungs and other organoids helping to beat COVID
Nature has recently published a news article talking about how mini lungs and other organoids helping to beat COVID. The article describes how researchers have built mini lungs, guts, livers, brains, and more to study how SARS-CoV-2 infects organs.Organoid technology...
Novel enzymes from the Arctic
From our roots to our unique enzymes - the Arctic is our home. Best-in-class novel enzymes Born from the unique conditions in the Arctic and our labs in Tromsø (Norway), we have been developing and producing cold-adapted enzymes for more than 30 years. Our...
Heat-labile Cod Uracil-DNA Glycosylase (UNG) for viral and other molecular diagnostic assays
Cod Uracil-DNA Glycosylase Cod Uracil-DNA Glycosylase (Cod UNG) from Atlantic cod is the only commercially available UNG enzyme that is completely and irreversibly inactivated by moderate heat treatment. The enzyme is produced in a recombinant E. coli (ung–)...
The only heat labile alkaline phosphatase originally isolated from arctic shrimp
Shrimp Alkaline Phosphatase ArcticZymes’ Shrimp Alkaline Phosphatase (SAP) is the only heat labile, all-purpose alkaline phosphatase purified from a recombinant source and originally isolated from Pandalus borealis (arctic shrimp). The recombinant production...
Looking to develop a COVID-19 test using RT-LAMP?
Currently there is a large demand for rapid and reliable point-of-care (POC) diagnostic tests for viral and bacterial pathogens to expedite clinical decision making and control disease spread. When establishing these new POC assays, the use of robust components...
New Distributorship Announcement – ArcticZymes Technologies
Effective 1 June 2021 LAB-A-PORTER Limited has been appointed as the official distributor of ArcticZymes Technologies. LAB-A-PORTER Limited will distribute and provide technical support for all ArcticZymes Technologies products and services to existing and new customers.
3D Printed Tumor Spheroids for Disease Modeling and Chemotherapeutic Drug Screening
Article OverviewCancer drug development is typically evaluated in conventional two-dimensional (2D) cell culture platforms. However, conventional 2D cultured cancer cells cannot mimic the complexity and heterogeneity of in-vivo tumors, which usually grow in a...
Development of Hypoxic-Responsive Lipid Polymer Nanoparticle for Eradication of Residual Glioma Cells
Article OverviewGlioma is the primary and most common type of intracranial tumor. Owing to their highly invasive nature and aggressive proliferation, it is difficult to completely excise gliomas to surgically cure glioma patients. As a result, there is a great need...
Inhibition of Scar Proliferation with In-situ Cross Bonding of VitroGel Hydrogel and Adipose-derived Stem Cells Conditioned Medium
Article OverviewHypertrophic scar (HS) is characterized by fibroblast over‐growth and excessive secretion of the extracellular matrix, which is a typical prognosis of tissue regeneration following dermal injuries. Acellular therapy based on stem cells provides a...
Cyclin-dependent kinase 7 (CDK7) Overexpression Implicated as an Independent Predictor of Poor Prognosis of Osteosarcoma
Article OverviewOsteosarcoma is the most common primary tumor of bone and accounts for 35% of primary bone malignancies. Survival rates in this disease have plateaued over the last four decades, as there has been a lack of emerging therapies showing clinical benefit....
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