BloG
Here finds you the updates from our reporter Dolly.
Role of neutrophil and PD-L1 pathway in wound healing of a burn injury
OverviewScience Advances has published an article discussing the role of neutrophil and programmed death ligand 1 (PD-L1) pathways in wound healing of a burn injury. Below are some highlighted topics from the article: • Importance of proactive infection control in...
Role of ORF8 and MHC-1 in T-cell antiviral immunity mechanism of COVID-19
OverviewCytotoxic T lymphocytes, also known as CD8+T cells, act a crucial role in regulating viral infection. They let out various toxic substances that can directly lead to the death of viral-infected cells. T cell receptors on cytotoxic T lymphocytes perceive...
Role of Ln-γ2 and TGF-β1 in anti-PD-1 therapy
OverviewThe PD-1/PD-L1 immune checkpoint plays an important role in serving immune escape for tumor cells. Tumor cells can bypass antitumor immunity by manipulating these immune checkpoints. In a research article from Frontier, the authors commented that immunotherapy...
Bio X Cell Back To School Promotion
To support your in vivo studies, Bio X Cell is thrilled to announce a special back-to-school discount for all products! From now until 30 September 2021, you could enjoy an additional 15% off on top of your academic discount. Limited offer. Grab the chance to stock up...
Blocking of Interleukin 7 (IL-7) signaling pathway reverses spot baldness
OverviewInterleukin-7 (IL-7) is a cytokine that has been known regarding its effects on T-cells and B-cells. Its signaling pathway has a crucial role in controlling T cell function and its survival. In the recent article published by Science Advances, the authors...
Anti-SARS-CoV-2 antibody inhibits variants of concern
OverviewbioRxiv has recently released a preprint discussing a compelling neutralizing anti-SARS-CoV-2 antibody that hinders variants of concern. The authors identified one monoclonal antibody (mAB), the SARS2-38, powerfully neutralizes all SARS-CoV-2 variants of...
5 reasons why ribonucleoproteins are a better alternative to CRISPR plasmids
Dr. Brittany Enzmann from Synthego has recently published an article discussing about why ribonucleoprotein (RNP) is a better alternative to CRISPR plasmids for CRISPR genome editing experiments. Below are highlights from the article:1. RNPs Reduce the Total...
How CRISPR editing is advancing cancer cell line research
Dr. Rebecca Roberts from Synthego has recently published an article discussing applications of CRISPR in cancer cell lines and how CRISPR editing is advancing cancer cell line research. The advent of CRISPR genome engineering technology has enabled many breakthroughs...
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[Webinar] Illumina – Mission Bio on novel somatic mutations
Webinar: Multiple Somatic Mutations Synergize to Drive Cerebral Cavernous Malformations In this webinar, Daniel Snellings from the Duke University Medical Centre shares the role of somatic mutations in the pathogenesis of vascular malformations with specific...
How PDL1-PD1 immune checkpoint inhibits T cell activation
OverviewScience Advance has recently published a research article discussing how the PDL1-PD1 immune checkpoint inhibits T cell activation. Checkpoint immunotherapy is known to be a revolutionizing treatment for previously refractive tumors. However, researchers had...
A review article about the molecular communication of SARS-CoV-2
OverviewSignal Transduction and Targeted Therapy has recently published a review article that reported the current expertise in the molecular communication of SARS-CoV-2. There is one session in the article specifically talking about small-molecule compound-based...
Organoids helping to defeat COVID
Nature has recently published a news article talking about how organoids helping to defeat COVID. The article describes how researchers have built mini-brains, guts, livers, lungs, and more to study how SARS-CoV-2 infects organs. Below are some highlights from the...
Novel enzymes from the Arctic
From our roots to our unique enzymes - the Arctic is our home. Best-in-class novel enzymes Born from the unique conditions in the Arctic and our labs in Tromsø (Norway), we have been developing and producing cold-adapted enzymes for more than 30 years. Our...
Heat-labile Cod Uracil-DNA Glycosylase (UNG) for viral and other molecular diagnostic assays
Cod Uracil-DNA Glycosylase Cod Uracil-DNA Glycosylase (Cod UNG) from Atlantic cod is the only commercially available UNG enzyme that is completely and irreversibly inactivated by moderate heat treatment. The enzyme is produced in a recombinant E. coli (ung–)...
The only heat labile alkaline phosphatase originally isolated from arctic shrimp
Shrimp Alkaline Phosphatase ArcticZymes’ Shrimp Alkaline Phosphatase (SAP) is the only heat labile, all-purpose alkaline phosphatase purified from a recombinant source and originally isolated from Pandalus borealis (arctic shrimp). The recombinant production...
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