BloG
Here finds you the updates from our reporter Dolly.
LAB-A-PORTER becomes the official distributor of OriGene in Hong Kong
Today, we are excited to announce that, LAB-A-PORTER becomes the official distributor of OriGene in Hong Kong. With this new partnership, we strive to bring premier sources for genomic and proteomic tools to researchers in Hong Kong. OriGene - Products at a...
Role of stem cells in the establishment of organoids and potential application of this model in cancer research
In nature, cells reside in tissues subject to complex cell-cell interactions, signals from extracellular molecules and niche soluble and mechanical signalling. These microenvironment interactions are responsible for cellular phenotypes and functions, especially in...
Role of organoid models on SARS-CoV-2 research, selected components for organoid culture recipes and more
Understanding the functional characteristics and cellular tropism of SARS-CoV-2, and the pathogenesis that leads to multi-organ failure and death has prompted an unprecedented adoption of organoid models. Successful drug discovery and vaccine development rely on...
Macrophages weaken TLR9 agonist antitumor activity through interacting with the anti-PD-1 antibody Fc domain
A combination of TLR9 agonists and an anti-PD-1 antibody has been reported effective in immunocompetent mice. However, the role of innate immunity has not yet been explained. In a recent article published by the Cancers, by using Bio X Cell’s anti-mouse PD-1 in vivo...
Webinar: Discovering novel immunological clues in small fiber neuropathy with innovative techniques
WEBINAR: Discovering novel immunological clues in small fiber neuropathy with innovative techniquesative-techniquesIn this webinar, Dr. Chan will review the current literature on autoimmunity in SFN, and her journey into discovering novel autoantibodies in idiopathic...
Quick review on colon organoids and colon epithelial organoid culture recipe
The Colon Organoids Using organoids as a model to study colorectal cancer Organoid limitations Organoids to study the intestinal microbiome and host-pathogen interactions Perspectives Selected compositions for colon epithelial organoid culture recipe by...
Scientists identified TRAPPC4 as a crucial PD-L1 regulator
Tumour cells escape T cell-mediated immunosurveillance through the interaction between programmed death (PD-1) ligand 1 (PD-L1) on tumour cells and PD-1 on T cells. Strategies disturbing PD-1/PD-L1 have shown clinical advantages in various cancers. However, the...
Some recent developments on gastric organoid research and gastric epithelial organoid culture recipe
The Gastric Organoids Challenges in research on human stomach and gastric cancer Opportunities on organoid technology in scientific research Application of gastric organoids in research Example on limitation of current organoid research Some future trends on...
Happy holidays!
LincRNA EPIC1 Mediates Immunotherapy Resistance
Bio X Cell has recently released a blog post talking about the role of LincRNA EPIC1 in cancer immunology. Below are the highlights from the blog post:The ability of tumour cells to evade immune detection plays a critical role in tumour development. Although...
Some recent developments on brain organoid research and brain organoid culture recipe
The Brain Organoids Challenges in research on the human brain Opportunities on organoid technology in scientific research Application of brain organoids in research Using brain organoids as models in research on ageing and brain tumour Future development of brain...
Post-event report: 26th Research Postgraduate Symposium @HKUMed
Thank you for visiting our booth at The 26th Research Postgraduate Symposium which was held on 1-2 December 2021 at the Li Ka Shing Faculty of Medicine of the University of Hong Kong. It was very insightful to learn about specific research needs from researchers and...
Facilitate your research on gastrointestinal epithelium cells with organoid cultures
The Intestinal Epithelium Organoid Cultures Challenges in establishing long-term systems for intestinal epithelium cultures Establishment of long-term gastrointestinal epithelium organoid culture The use of small molecules in intestinal organoid culture Building of...
Preventing Breast Cancer Metastasis: A Role for Cathepsin C Inhibitors
Bio X Cell has recently released a blog post talking about the role of cathepsin c inhibitors in cancer metastasis. Below are the highlights from the blog post:Breast cancer deaths are often the result of metastasis to distant organs including the lungs. Overcoming...
A quick review on current development of pancreatic organoids
Organoids – the past, present and the futureOrganoid models are known for their thrilling opportunities and potential for scientists in studying developmental processes, drug testing and disease modelling, including genetic, developmental disorder, degenerative...
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