CRISRP Articles

COVID-19 Research Impact Report

Moving Research Forward During COVID-19 and BeyondThe COVID-19 pandemic impacted thousands of scientists across the globe, bringing important research projects to a standstill. Synthego is actively collaborating with scientists working on COVID-19 projects during this...

CRISPR Gene Editing in iPS Cells

Induced pluripotent stem (iPS) cells are one of the most valuable tools in biomedical research. These special cells originate from regular somatic cells, like those comprising skin. By ectopically expressing key transcription factors, the cells are reprogrammed to a...

RNAi vs. CRISPR: Guide to Selecting the Best Gene Silencing Method

The process for drug discovery and therapeutic development heavily relies on correlating genotype to phenotype. The best way to achieve this is to disrupt gene function and analyze its phenotypic. Researchers can experimentally regulate gene expression and interrogate...

CRISPR: Knockouts For Loss-of-Function Experiments

History of CRISPR The foundational discoveries leading to the development of CRISPR-Cas9 technology date back to 1987, when researchers first identified palindromic segments of DNA in bacteria. At the time, the significance of these Clustered Regularly Interspaced...