Cancer Articles

How CRISPR editing is advancing cancer cell line research

Dr. Rebecca Roberts from Synthego has recently published an article discussing applications of CRISPR in cancer cell lines and how CRISPR editing is advancing cancer cell line research. The advent of CRISPR genome engineering technology has enabled many breakthroughs...

Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells

OverviewScience Advances has recently published a research article discussing how the PDL1-PD1 immune checkpoint inhibits T cell activation. Checkpoint immunotherapy is known to be a revolutionizing treatment for previously refractive tumors. However, researchers had...

Single-cell DNA Analysis in Cancer Research and the Potential of Dynamic Therapy

Dr. Catherine Smith is a physician-scientist and an Assistant Professor in the Department of Medicine at UCSF. Her lab in the Division of Hematology/Oncology is focused on a subtype of AML (acute myeloid leukemia) characterized by mutations in FLT3, a gene that is...

Penetrating Cancer Stem Cells For Lung Cancer Treatment

Lung cancer is the leading cause of cancer-related mortality worldwide. Despite the recent advances in cancer research, about 70% of the patients with lung cancer present with locally advanced or metastatic disease at the time of the diagnosis. Although chemotherapy...