<p>Dr. Brittany Enzmann from Synthego has recently published an article discussing about why ribonucleoprotein (RNP) is a better alternative to CRISPR plasmids for CRISPR genome editing experiments. Below are highlights from the article: 1. RNPs Reduce the Total Experimental Time Plasmid-based CRISPR transfection requires multiple steps for the guide preparation and is more labor-intensive compared […]</p>

<p>Dr. Rebecca Roberts from Synthego has recently published an article discussing applications of CRISPR in cancer cell lines and how CRISPR editing is advancing cancer cell line research. The advent of CRISPR genome engineering technology has enabled many breakthroughs in the field of oncology. The author has looked into some of the key examples of CRISPR […]</p>

<p>Webinar: Multiple Somatic Mutations Synergize to Drive Cerebral Cavernous Malformations   In this webinar, Daniel Snellings from the Duke University Medical Centre shares the role of somatic mutations in the pathogenesis of vascular malformations with specific focus on Cerebral Cavernous Malformations, Hereditary Hemorrhagic Telangiectasia, and Sturge-Weber Syndrome. The goal of his work is to identify […]</p>

<p>Overview Science Advances has recently published a research article discussing how the PDL1-PD1 immune checkpoint inhibits T cell activation. Checkpoint immunotherapy is known to be a revolutionizing treatment for previously refractive tumors. However, researchers had found that only a portion of patients responded, and some responders gained resistance. In the article, researchers were inspecting how […]</p>

<p>Overview Signal Transduction and Targeted Therapy has recently published a review article that reported the current expertise about how SARS-CoV-2 attaches on the surface of host cells through a variety of receptors, such as ACE2, neuropilin-1, AXL, and antibody-FcyR complexes. In the article, researchers illustrated how its spike (S) protein has a conformational transition from […]</p>

<p>Nature has recently published a news article talking about how mini lungs and other organoids helping to beat COVID. The article describes how researchers have built mini lungs, guts, livers, brains, and more to study how SARS-CoV-2 infects organs. Organoid technology and its potential usage Organoid technology had previously been utilized mainly to examine basic […]</p>

<p>The Arctic has shaped usFrom our roots to our unique enzymes – the Arctic is our home. Best-in-class novel enzymes   Born from the unique conditions in the Arctic and our labs in Tromsø (Norway), we have been developing and producing cold-adapted enzymes for more than 30 years. Our high-quality enzymes are an integral part […]</p>

<p>Cod Uracil-DNA Glycosylase   Cod Uracil-DNA Glycosylase (Cod UNG) from Atlantic cod is the only commercially available UNG enzyme that is completely and irreversibly inactivated by moderate heat treatment. The enzyme is produced in a recombinant E. coli (ung–) strain that contains a modified Cod UNG gene. Heat-labile Completely and irreversibly inactivated at 55°C Contamination […]</p>

<p>Shrimp Alkaline Phosphatase   ArcticZymes’ Shrimp Alkaline Phosphatase (SAP) is the only heat labile, all-purpose alkaline phosphatase purified from a recombinant source and originally isolated from Pandalus borealis (arctic shrimp). The recombinant production leads to increased storage stability, low batch-to-batch variations and high specific activity. For added flexibility, when lyophilization may be desired, SAP is […]</p>

<p>Currently there is a large demand for rapid and reliable point-of-care (POC) diagnostic tests for viral and bacterial pathogens to expedite clinical decision making and control disease spread. When establishing these new POC assays, the use of robust components allowing amplification directly from biological sample material is essential.   ArcticZymes Technologies launches new optimized IsoPol […]</p>