<p>VISIT OUR BOOTH AT 26th Research Postgraduate Symposium1-2 December 2021 @HKUMed The 26th Research Postgraduate Symposium organized by Li Ka Shing Faculty of Medicine of the University of Hong Kong will be held on 1-2 December 2021. We are excited to be exhibiting as Prize Sponsor at this event.   Come and visit our booth […]</p>

<p>The Intestinal Epithelium Organoid Cultures Challenges in establishing long-term systems for intestinal epithelium cultures Establishment of long-term gastrointestinal epithelium organoid culture The use of small molecules in intestinal organoid culture Building of gut organoids Cytokines used in long-term gastrointestinal epithelium culture Small molecules and peptides used in gastrointestinal culture Challenges in establishing long-term systems for […]</p>

<p>Breast cancer deaths are often the result of metastasis to distant organs including the lungs. Overcoming inhibitory mechanisms and establishing growth in new microenvironments is critical to the metastatic process. Using anti-mouse IL-1b (clone B122) and anti-mouse IL-6 (clone MP5-20F3) antibodies from Bio X Cell, researchers have described a role for the tumour-secreted protease, cathepsin […]</p>

<p>Organoids – the past, present and the future Organoid models are known for their thrilling opportunities and potential for scientists in studying developmental processes, drug testing and disease modelling, including genetic, developmental disorder, degenerative disorders, and cancer. Past The earliest 3D organoid models were first reported over 40 years ago [1]. Early organoid models demanded […]</p>

<p>Overview Science Advances has published an article discussing the role of neutrophil and programmed death ligand 1 (PD-L1) pathways in wound healing of a burn injury. Below are some highlighted topics from the article: • Importance of proactive infection control in burn injury• Role of neutrophils in a burn injury• Programmed death ligand 1 (PD-L1) […]</p>

<p>Overview Cytotoxic T lymphocytes, also known as CD8+T cells, act a crucial role in regulating viral infection. They let out various toxic substances that can directly lead to the death of viral-infected cells. T cell receptors on cytotoxic T lymphocytes perceive signals given by MHC-Ι–peptide complex, eliminating cells that are responsible for viral replication and […]</p>

<p>Overview The PD-1/PD-L1 immune checkpoint plays an important role in serving immune escape for tumor cells. Tumor cells can bypass antitumor immunity by manipulating these immune checkpoints. In a research article from Frontier, the authors commented that immunotherapy targeting on PD1/PDL1 axis can effectively block its pro-tumor activity; however, only a subset of patients can […]</p>

<p>To support your in vivo studies, Bio X Cell is thrilled to announce a special back-to-school discount for all products! From now until 30 September 2021, you could enjoy an additional 15% off on top of your academic discount. Limited offer. Grab the chance to stock up your in vivo antibodies and jump-start your research! Get Quote Now Our top […]</p>

<p>Overview Interleukin-7 (IL-7) is a cytokine that has been known regarding its effects on T-cells and B-cells. Its signaling pathway has a crucial role in controlling T cell function and its survival. In the recent article published by Science Advances, the authors identified:   Overexpression of IL-7 in lesional skin from both humans and mice […]</p>

<p>Overview bioRxiv has recently released a preprint discussing a compelling neutralizing anti-SARS-CoV-2 antibody that hinders variants of concern. The authors identified one monoclonal antibody (mAB), the SARS2-38, powerfully neutralizes all SARS-CoV-2 variants of concern tested and protects mice against challenge by multiple SARS-CoV-2 strains. In the preprint, the structural analysis demonstrated that SARS2-38 employs a […]</p>