5 reasons why ribonucleoproteins are a better alternative to CRISPR plasmids

by Dolly the Sheep | Jul 28, 2021 | CRISRP

Dr. Brittany Enzmann from Synthego has recently published an article discussing about why ribonucleoprotein (RNP) is a better alternative to CRISPR plasmids for CRISPR genome editing experiments. Below are highlights from the article: 1. RNPs Reduce the Total...

How CRISPR editing is advancing cancer cell line research

by Dolly the Sheep | Jul 28, 2021 | Cancer, CRISRP

Dr. Rebecca Roberts from Synthego has recently published an article discussing applications of CRISPR in cancer cell lines and how CRISPR editing is advancing cancer cell line research. The advent of CRISPR genome engineering technology has enabled many breakthroughs...

[Webinar] Illumina – Mission Bio on novel somatic mutations

by Dolly the Sheep | Jul 21, 2021 | News, NGS, Single Cell

Webinar: Multiple Somatic Mutations Synergize to Drive Cerebral Cavernous Malformations   In this webinar, Daniel Snellings from the Duke University Medical Centre shares the role of somatic mutations in the pathogenesis of vascular malformations with specific...

Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells

by Dolly the Sheep | Jul 12, 2021 | Cancer, in vivo Studies

Overview Science Advances has recently published a research article discussing how the PDL1-PD1 immune checkpoint inhibits T cell activation. Checkpoint immunotherapy is known to be a revolutionizing treatment for previously refractive tumors. However, researchers had...

Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy

by Dolly the Sheep | Jul 5, 2021 | COVID-19

Overview Signal Transduction and Targeted Therapy has recently published a review article that reported the current expertise about how SARS-CoV-2 attaches on the surface of host cells through a variety of receptors, such as ACE2, neuropilin-1, AXL, and antibody-FcyR...