by Dolly the Sheep | May 8, 2020 | CRISRP, Technology
History of CRISPR The foundational discoveries leading to the development of CRISPR-Cas9 technology date back to 1987, when researchers first identified palindromic segments of DNA in bacteria. At the time, the significance of these Clustered Regularly Interspaced...
by Dolly the Sheep | May 8, 2020 | CRISRP, Technology
History of RNAi In 1990, researchers noticed for the first time that RNA could potentially suppress gene expression in plants. The underlying mechanism of this “erratic and reversible” gene suppression was not clear. It wasn’t until almost a decade later...
by Dolly the Sheep | May 5, 2020 | COVID-19, Technology
BioGems is proud to offer a targeted portfolio of small molecules for life science research. Small molecules are low molecule weight organic compounds that affect key biological pathways to allow for the control of cellular responses. Their small size allows them to...
by Dolly the Sheep | Apr 28, 2020 | COVID-19, CRISRP, Technology
The COVID-19 pandemic has led to an urgent response from the research and scientific community around the world. The scientific community needs innovative tools that enable rapid development of COVID-19 diagnostics, therapeutics, and vaccines. Synthego is supporting...
by Dolly the Sheep | Apr 20, 2020 | Cancer, Immunology, Immunotherapy, in vivo Studies
Lymphocyte-activation gene 3 (LAG-3) is a receptor that negatively regulates the proliferation, activation, and effector function of T cells. Currently, monoclonal antibodies that block the interaction of LAG-3 with its canonical ligand, MHC-II, are being evaluated...
