in vivo Studies Articles

Role of neutrophil and PD-L1 pathway in wound healing of a burn injury

OverviewScience Advances has published an article discussing the role of neutrophil and programmed death ligand 1 (PD-L1) pathways in wound healing of a burn injury. Below are some highlighted topics from the article: • Importance of proactive infection control in...

Role of Ln-γ2 and TGF-β1 in anti-PD-1 therapy

OverviewThe PD-1/PD-L1 immune checkpoint plays an important role in serving immune escape for tumor cells. Tumor cells can bypass antitumor immunity by manipulating these immune checkpoints. In a research article from Frontier, the authors commented that immunotherapy...

Blocking of Interleukin 7 (IL-7) signaling pathway reverses spot baldness

OverviewInterleukin-7 (IL-7) is a cytokine that has been known regarding its effects on T-cells and B-cells. Its signaling pathway has a crucial role in controlling T cell function and its survival. In the recent article published by Science Advances, the authors...

Anti-SARS-CoV-2 antibody inhibits variants of concern

OverviewbioRxiv has recently released a preprint discussing a compelling neutralizing anti-SARS-CoV-2 antibody that hinders variants of concern. The authors identified one monoclonal antibody (mAB), the SARS2-38, powerfully neutralizes all SARS-CoV-2 variants of...