in vivo Studies Articles

InVivoMAb anti-mouse NKG2D (CD314) (Clone: CX5) Useful for in vivo and in vitro  NKG2D blockade The CX5 monoclonal antibody reacts with mouse NKG2D, a type II transmembrane lectin-like glycoprotein also known as CD314. NKG2D is expressed on NK cells, NKT cells, CD8 T...

Immune checkpoint proteins play a fundamental role in regulating T cell responses during viral infections. On one hand, they need to promote T cell functions in order to clear the virus. On the other hand, they need to restrict T cell activity to prevent...

Lymphocyte-activation gene 3 (LAG-3) is a receptor that negatively regulates the proliferation, activation, and effector function of T cells. Currently, monoclonal antibodies that block the interaction of LAG-3 with its canonical ligand, MHC-II, are being evaluated...

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