BloG
Here finds you our updates from our reporter Dolly.
Tips For Scientists to Effectively Work from Home
Social distancing and shelter-in-place orders currently in effect in response to the COVID-19 crisis have upturned work patterns of companies and academics alike. With several labs shutting down and grinding experiments to an abrupt halt, scientists find themselves...
Organoids – Mini organs in a dish
Organoid models include three-dimensional (3D) cell culture systems that closely resemble the in vivo organ or tissue from which they are derived. These 3D systems replicate the complex spatial morphology of a differentiated tissue, and allow biologically relevant...
Stem Cells: Links to Human Cancer and Aging
The human body develops from a single diploid cell called a zygote and contains at adulthood an estimated 85 trillion cells, of which more than 150 billion turn over every day. All of these cells originate from a tiny population of so-called "embryonic" and "adult"...
Targeting sphingolipid metabolism enhances cancer immunotherapy
CTLA-4 and PD-1 based immunotherapies have demonstrated significant clinical efficacy in melanoma patients, but many patients remain non-responsive and relapse is common. To try and improve the response rate, researchers are currently working to develop innovative...
Bio X Cell New Product – InVivoMAb anti-rat/mouse CD71 (TfR1)
InVivoMAb anti-rat/mouse CD71 (TfR1) Useful for targeted drug delivery to the brain The OX-26 monoclonal antibody reacts with rat CD71 also known as transferrin receptor protein 1 (TfR1). The antibody is reported to cross-react with mouse CD71 as well. CD71 is a...
PeproTech 20% Off Flow Cytometry Products
20% Discount on All Flow Cytometry Products To better support your research, PeproTech is now offering 20% off discount for all the Flow Cytometry products. Select your target by clicking the link below. Flow Cytometry Antibodies SAFIRE Antibodies Purified anti CD...
Coronavirus Detection Using CRISPR Technology
There is no dearth of materials around the potential of CRISPR and how it is already impacting medicine, food, biomaterials—basically our everyday lives. With researchers putting their best foot forward globally to fight the recent novel coronavirus outbreak, one...
Bio X Cell Launch Promotion
10% Discount on All AntibodiesTo celebrate our exclusive partnership with Bio X Cell, we are thrilled to announce a special launching discount for all in vivo antibodies! From now until 31 March 2020, you could enjoy an additional 10% off on top of your academic...
Lab-grown Burger and the Clean Meat Future
What is Clean meat Clean meat is meat that is obtained through in-vitro culture growth, rather than from living animals. This type of meat is also known by various alternative names, such as "Cultured Meat" "Artificial Meat" "In-vitro Meat" and "Cell-grown meat" to...
Cell Engineering 101 – A step-by-step guide to CRISPR knockouts
A step-by-step guide to CRISPR knockouts CRISPR has ignited a revolution. Although it’s a relatively recent discovery in the history of biotechnology, CRISPR has quickly become a standard laboratory tool and cell engineering is transforming research. One of the most...
What are Immune Checkpoints?
What are Immune Checkpoints? Immune checkpoints are regulators of the immune system which prevent the immune system from attacking self-antigens indiscriminately. While this is critical to preventing auto-immune disease it also causes the immune system to be...
Prophylactic treatment with antagonistic anti-TNFα antibodies may improve outcomes of anti-PD-1 and anti-CTLA-4 combination cancer immunotherapy
The combination of anti-PD-1 and anti-CTLA-4 antibody-mediated immunotherapy is remarkably effective against melanoma, renal cell carcinoma, and non-small-cell lung cancer. However, this comes at the cost of frequent, serious immune-related adverse events. Colitis is...
New Distributorship Announcement – Bio X Cell
in vivo GRADE ANTIBODIES AT UNMATCHED PRICEEffective 1 January 2020 LAB-A-PORTER Limited has been appointed as the official exclusive distributor of Bio X Cell. LAB-A-PORTER Limited will distribute and provide technical support for all Bio X Cell products and services...
Immune Checkpoints and Co-stimulators
Facilitate Your Immune Regulations StudyThe recognition of the antigenic peptide-MHC I/II complex on antigen presenting cells (APCs) through the T cell receptor (TCR) initiates T cell-mediated immunity. However, the interaction of antigen-MHC complexes with the TCR is...
Guided Edit Interactive Tool: A Step-by-Step Guide to Choose the Best CRISPR Solution
CRISPR has gone from a new tool to one of the most important discoveries in the world of biology. The applications of CRISPR are endless, and there is a plethora of information out there on how this tool can be used in different ways. But Synthego knows that too much...
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