BloG
Here finds you the updates from our reporter Dolly.
Bio X Cell New Product – 𝙄𝙣𝙑𝙞𝙫𝙤MAb anti-mouse NKG2D (CD314) (Clone CX5)
InVivoMAb anti-mouse NKG2D (CD314) (Clone: CX5) Useful for in vivo and in vitro NKG2D blockade The CX5 monoclonal antibody reacts with mouse NKG2D, a type II transmembrane lectin-like glycoprotein also known as CD314. NKG2D is expressed on NK cells, NKT cells, CD8 T...
CRISPR Gene Editing in iPS Cells
Induced pluripotent stem (iPS) cells are one of the most valuable tools in biomedical research. These special cells originate from regular somatic cells, like those comprising skin. By ectopically expressing key transcription factors, the cells are reprogrammed to a...
TIGIT Limits Immune Pathology During Viral Infection
Immune checkpoint proteins play a fundamental role in regulating T cell responses during viral infections. On one hand, they need to promote T cell functions in order to clear the virus. On the other hand, they need to restrict T cell activity to prevent...
Organoid models suggest SARS-CoV-2 infects human intestinal cells
A research group at the Hubrecht Institute, Erasmus MC University Medical Centre, and Maastricht University in the Netherlands used 3D intestine organoids to elucidate the infection pathway of SARS-CoV-2, the virus that caused COVID-19. Their findings may shed light...
PeproTech Media Products
PeproTech’s line of PeproGrow™ Cell Culture Media, Media Supplements and Companion Products are aimed at supporting your culturing needs. With these products we strive to redefine the quality of culture media and media companion products while continuing to offer...
AML Subpopulations Defined by SNV, CNV, and Protein Expression
Single-cell Multi-omics Enables Granular Resolution Into AML For Powerful Insight Into the Correlation Between Genotype and PhenotypeTakeaways Tapestri Platform is the only single- cell multi-omics platform capable of simultaneously detecting SNVs, CNVs, and protein...
Summer Promotion – Free Cell Freezing Container
LAB-A-PORTER and PeproTech are supporting your research as always! From now till 20 June 2020, you will be awarded for a 12-well Cell Freezing Container by ordering >HKD$3,000 PeproTech products. Limited offer. Grab the chance before the gift is gone! Signature...
RNAi vs. CRISPR: Guide to Selecting the Best Gene Silencing Method
The process for drug discovery and therapeutic development heavily relies on correlating genotype to phenotype. The best way to achieve this is to disrupt gene function and analyze its phenotypic. Researchers can experimentally regulate gene expression and interrogate...
CRISPR: Knockouts For Loss-of-Function Experiments
History of CRISPR The foundational discoveries leading to the development of CRISPR-Cas9 technology date back to 1987, when researchers first identified palindromic segments of DNA in bacteria. At the time, the significance of these Clustered Regularly Interspaced...
RNAi: The Knockdown Pioneer
History of RNAi In 1990, researchers noticed for the first time that RNA could potentially suppress gene expression in plants. The underlying mechanism of this “erratic and reversible” gene suppression was not clear. It wasn’t until almost a decade later...
Small Molecules for COVID-19 Research
BioGems is proud to offer a targeted portfolio of small molecules for life science research. Small molecules are low molecule weight organic compounds that affect key biological pathways to allow for the control of cellular responses. Their small size allows them to...
CRISPR Tools to Accelerate COVID-19 Research and Development
The COVID-19 pandemic has led to an urgent response from the research and scientific community around the world. The scientific community needs innovative tools that enable rapid development of COVID-19 diagnostics, therapeutics, and vaccines. Synthego is supporting...
Anti-tumor T cell responses through LAG-3 blockade
Lymphocyte-activation gene 3 (LAG-3) is a receptor that negatively regulates the proliferation, activation, and effector function of T cells. Currently, monoclonal antibodies that block the interaction of LAG-3 with its canonical ligand, MHC-II, are being evaluated...
CRISPR Benchmark Report
CRISPR is easily one of the most popular tools in modern biology. Since its introduction in 2012, CRISPR-based publications have increased about 30 fold. With NIH funding for CRISPR-related projects per year crossing a billion dollars in 2020, it is safe to assume...
New Distributorship Announcement – The Well Bioscience
VITROGEL® HYDROGEL User-friendly and robust hydrogel for 3D cell culture research Effective 1 April 2020 LAB-A-PORTER Limited has been appointed as the official exclusive distributor of The Well Bioscience. LAB-A-PORTER Limited will distribute and provide technical...
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