Product Highlights: An EtBr alternative – RedSafe™ Nucleic Acid Staining Solution from iNtRON Biotechnology

by | Apr 23, 2024 | Cancer, Immunology, in vivo Studies, Neurology

ABOUT iNtRON Biotechnology

Research Use Reagents on Genomics, Proteomics and Cell Culture

Based in Korea, with an international office in Boston, US, iNtRON Biotechnology provides various research-use-only tools on genomic research, proteomic research and cell culture, specializing products in nucleic acid extraction and amplifications, protein extraction,  as well as mycoplasma detection and prevention. Key products include:

  • Genomic DNA Extraction Kits
  • Plasmid DNA Purification Kits
  • RNA Extraction Kits
  • Protein Extraction Solution and Western Blot Detection System
  • Tools for PCR, RT-PCR and Real-time PCR
  • Mycoplasma PCR Detection Kits and Mycoplasma Prevention Spray

PRODUCT HIGHLIGHT FROM INTRON BIOTECHNOLOGY

RedSafe™ Nucleic Acid Staining Solution 

RedSafe Nucleic Acid Staining Solution (20,000x) is an alternative to the traditional ethidium bromide (EtBr) stain for detecting nuclei acid in agarose gels. It emits green fluorescence when bound to DNA or RNA. This new stain has two fluorescence excitation maxima when bound to nucleic acid, one centered at 309nm and another at 419nm. In addition, it has one visible excitation at 514nm. The fluorescence emission of RedSafebound to DNA is centered at 537nm.

RedSafe Nucleic Acid Statining Solution (20,000x) is as sensitive as EtBr. The staining protocol for RedSafe Nucleic Acid Statining Solution (20,000x) is similar to that for EtBr.

Compared to EtBr, known as a strong mutagen, RedSafe Nucleic Acid Statining Solution (20,000x) causes much fewer mutations in the Ames test. In addition, RedSafe Nucleic Acid Statining Solution (20,000x) has a negative result in mouse marrow chromophilous erythrocyte micrinucleus test and mouse spermary spermatocyte chromosomal aberration test.

Characteristics

  • Used for detecting double-strand DNA and single-stranded RNA
  • Alternative to the ethidium bromide staining
  • As sensitive as EtBr or more sensitive than that
  • Non-toxic, non-mutagenic and non-carcinogenic
  • No hazard waste

*All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.

References:

  1. iNtRON Biotechnology, ‘Protocol: RedSafe Nucleic Acid Statining Solution (20,000x)’. Available at https://intronbio.com:6001/inc/downfile.php?filename=F1524025893.pdf&orgfilename=IDR-RP0110_RedSafe.pdf&filedir=product_protocol
  2. iNtRON Biotechnology, ‘MSDS: RedSafe Nucleic Acid Statining Solution (20,000x)’. Available at https://intronbio.com:6001/inc/downfile.php?filename=F1528175766.pdf&orgfilename=RedSafe.pdf&filedir=product_msds

Learn more on our comprehensive research reagents today.

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