QKINE

Based in Cambridge, UK, Qkine combines proprietary protein production processes with protein engineering techniques to develop unique growth factors. These proteins tackle fundamental biological and scale-up challenges for the fast-growing stem cell, organoid, and cellular agriculture sectors.

ABOUT THE SUPPLIER

A UK Manufacturer Provides Cost-Effective Highly Bioactive Growth Factors For Stem Cell and Organoid Research

Based in Cambridge, UK, Qkine combines proprietary protein production processes with protein engineering techniques to develop unique growth factors. These proteins tackle fundamental biological and scale-up challenges for the fast-growing stem cell, organoid, and cellular agriculture sectors.

Qkine has an active R&D pipeline, with a continually expanding product range. Unique products available from Qkine include tag-free thermostable FGF-2 (FGF2-G3), the first animal-free TGF-β1 for chemically defined stem cell media, and animal-free HGF (NK1).

Qkine is an ISO 9001: 2015 certified company.

PRODUCT FEATURES

 

Qkine manufactures high-purity, animal-free growth factors, cytokines and other complex proteins for stem cell and organoid culture. An ISO 9001: 2015 certified company based in Cambridge, UK, Qkine combines proprietary production processes with protein engineering technology to tackle fundamental biological and scale-up challenges.

  • Highly bioactive 
  • Animal-free to eliminate the risks of contaminating growth factors, viruses, and prions
  • Manufactured in UK
  • Clear QC data provided on every lot from our ISO 9001:2015 accredited facility
  • Excellent lot-to-lot consistency to help increase the reproducibility of experiments
  • High purity confirmed by several varied techniques, ensuring the reliability of results
  • Long-term stability
  • Multiple pack sizes to suit your research

NEW RELEASENew

Growth factors & cytokines for cellular agriculture & cultivated meat research

Growth factors are critical components of cell culture media and provide a carefully orchestrated set of biochemical signals to control cell growth and fate. High purity, animal-free and optimized growth factors produced in an efficient microbial fermentation process provide solutions for cultivated meat and cellular agriculture.

Qkine has recently released 4 new products for cellular agriculutre & cultivated meat research:

Recombinant salmon FGF-2 (154 aa) protein (Qk103)

Recombinant salmon FGF-2 (145 aa) protein (Qk102)

Recombinant bovine/porcine FGF2-G3 154 aa protein (Qk081)

Recombinant bovine/porcine FGF2-G3 145 aa protein (Qk080)

Growth factor discovery kits for cellular agriculture research

 

Introducing Qkine’s new growth factor discovery kits to help cellular agriculture research.

FGF-2 species-specific discovery kit (Qk501)

Thermostable FGF-2 discovery kit (Qk502)

B8 media discovery kit (Qk503) 

Beefy9 media growth factor discovery kit (Qk504) 

Serum-free media optimization growth factor discovery kit (Qk505) 

Recombinant human IL-4 protein (Qk092)

Human IL-4 has a molecular weight of 15.1 kDa. This protein is carrier-free and tag-free to ensure its purity with exceptional lot-to-lot consistency. Qk092 is suitable for the culture of reproducible and high-quality stem cells and other relevant cells.

Recombinant human IL-6 protein (Qk093)

Human IL-6 has a molecular weight of 20.9 kDa. This protein is carrier-free and tag-free to ensure its purity with exceptional lot-to-lot consistency. Interleukin-6 is suitable for the culture of reproducible and high-quality hematopoietic stem cells and other relevant cells.

Recombinant human SCF protein (Qk078)

Qkine has optimised the SCF manufacture process to produce a highly bioactive protein with excellent lot-to-lot consistency for enhanced experimental reproducibility. Recombinant SCF is a highly pure 18.5 kDa monomer, animal-free (AOF) and carrier-protein-free (CF).

Recombinant human/bovine/porcine TGF-β2 protein (Qk072)

TGF-beta 2 is a high purity protein with a molecular weight of 25.4 kDa. This protein is carrier-free and tag-free to ensure its purity with exceptional lot-to-lot consistency. Qkine TGF-beta 2 is suitable for the culture of reproducible and high-quality stem cells and other relevant cells.

Recombinant human DKK-1 protein (Qk068)

Human DKK-1 has a molecular weight of 25.7 kDa. This protein is carrier-free and tag-free to ensure its purity with exceptional lot-to-lot consistency. DKK1 is suitable for the culture of reproducible and high-quality stem cells and other relevant cells.

Recombinant mouse EGF protein (Qk066)

Mouse EGF is a high purity protein with a molecular weight of 6.1 kDA. This protein is carrier-free and tag-free to ensure its purity with exceptional lot-to-lot consistency. Qkine mouse EGF is suitable for the culture of reproducible and high-quality stem cells and various tissue-specific organoids.

FEATURED PRODUCTS

Recombinant human R-spondin 1 protein (Qk006)

Qk006 is animal-free and not glycosylated to ensure production of homogeneous protein and enhanced comparability between batches. Used to replace R-spondin conditioned media for improved reproducibility in chemically defined organoid culture media.

Recombinant human/rat/bovine/porcine FGF-10 protein (Qk003)

High purity and bioactivity 17 kDa non-glycosylated, bioactive domain of human fibroblast growth factor 10, animal-derived component free (ACDF) and carrier-protein free (CF).

Recombinant human noggin protein (Qk034)

Qkine human noggin protein is a highly pure 46kDa bioactive dimer for reproducible results in organoid culture.

Recombinant human HGF (NK1) protein (Qk013)

Human HGF (NK1) protein is a potent, high purity NK1 isoform of human hepatocyte growth factor (HGF) that promotes efficient differentiation of human iPSCs to hepatocyte-like cells at just 10 ng/ml with highly homogeneous expression of the hepatic marker, HNF4α. 

*All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.

PRODUCT APPLICATIONS

Organoids

Growth factors for defined organoid culture media

Human Stem Cell Maintenance

Maintenance of pluripotency in human iPSC and ESC

Neural Stem Cell Culture

Growth factors and cytokines for neural stem cell and brain organoid culture

Mouse Stem Cell Maintenance

Maintenance of pluripotency in mouse stem cells

Hepatocyte Differentiations

Complete animal-free hepatocyte differentiation process

OUR TOP PRODUCT PICKS

 

A

Activin A – human/mouse/rat/bovine/porcine (Qk001)

Activin A PLUS – human/mouse/rat/bovine/porcine (Qk005)

Activin A follistatin-resistant – human/mouse/rat (Qk035)

B

BDNF – human (Qk050)

BMP-2 – human/mouse/rat/bovine/porcine (Qk007)

BMP-4 – human (Qk038)

C

CNTF – human (Qk063)

D

DKK-1 – human (Qk068)

E

EGF – human  (Qk011)

EGF – porcine  (Qk064)

EGF – mouse (Qk066)

F

FGF1-human (Qk071)

FGF-2-G3 (thermostable) 154aa (Qk053)

FGF2-G3 (thermostable) 145aa (Qk052)

FGF-2 (bFGF) 154aa – human (Qk027)

FGF- 2(bFGF) 145aa – human  (Qk025)

FGF- 2(bFGF) – zebrafish   (Qk002)

FGF- 2(bFGF) – mouse (Qk042)

FGF- 2(bFGF) 145aa – bovine/porcine (Qk040)

FGF- 2(bFGF) 154aa – bovine/porcine (Qk056)

FGF-2 (154 aa) – salmon (Qk103)

FGF-2 (145 aa)  – salmon (Qk102)

FGF2-G3 154 aa – bovine/porcine (Qk081)

FGF2-G3 145 aa – bovine/porcine(Qk080)

FGF-4 – human (Qk004)

FGF-8a – human/mouse (Qk059)

FGF-8b – human/mouse (Qk057)

FGF-9 – human (Qk039)

FGF-10 – human/rat/bovine/porcine (Qk003)

Flt3L – human (Qk087)

FRACTA – human/mouse/rat/bovine/porcine (Qk035)

G

GDF5-human (Qk070)

GDF15 – human (Qk017)

GDNF – human (Qk051)

GM-CSF (Qk076)

Gremlin 1 – human/bovine/porcine (Qk015)

G-CSF – human (Qk074)

H

HGF (NK1) – human (Qk060)

HGF (NK1) – bovine (Qk061)

HGF (NK1) – porcine (Qk013)

I

IGF-1 – human/bovine/porcine (Qk047)

IGF-1 LR3 – human/bovine/porcine (Qk041)

IL-1 beta – human (Qk101)

IL-3 – human (Qk090)

IL-4 – human (Qk092)

IL-6 – human (Qk093)

K

KGF (FGF-7) – human (Qk046)

L

LIF – human (Qk036)

LIF – mouse (Qk018)

M

M-CSF – human (Qk075)

N

Noggin – human (Qk034)

Noggin – mouse/rat (Qk033)

NGR-1 – human/bovine/porcine (Qk045)

NT-3 – human/mouse/rat/porcine (Qk058)

O

OSM – human(Qk049)

P

PDGF-AA – human (Qk043)

PDGF-BB – human (Qk044)

R

R-Spondin-1 – human (Qk006)

R-Spondin- 1 LR5 – human (Qk031)

R-Spondin 3 – human (Qk032)

S

SCF – human (Qk078)

Shh – human (Qk055)

T

TNF-alpha – human (Qk083)

TGF-beta1 PLUS – human/bovine/porcine (Qk010)

TGF-beta2 – human/bovine/porcine (Qk072)

TGF-beta3 – human (Qk054)

V

VEGF 165- human  (Qk048)

Discovery kits

FGF-2 species-specific discovery kit (Qk501)

Thermostable FGF-2 discovery kit (Qk502)

B8 media discovery kit (Qk503) 

Beefy9 media growth factor discovery kit (Qk504) 

Serum-free media optimization growth factor discovery kit (Qk505) 

*All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.

IF YOU NEED COST-EFFECTIVE HIGHLY BIOACTIVE GROWTH FACTORS, WE CAN HELP.

Contact us