Cost-effective growth factors for stem cell research


Qkine manufactures high-purity, animal-free growth factors, cytokines and other complex proteins for stem cell and organoid culture. An ISO 9001: 2015 certified company based in Cambridge, UK, Qkine combines proprietary production processes with protein engineering technology to tackle fundamental biological and scale-up challenges.


    • High lot-to-lot consistency to help increase the reproducibility of experiments
    • Animal-free to eliminate the risks of contaminating growth factors, viruses, and prions
    • Ultra-pure confirmed by several varied techniques, ensuring the reliability of results
    • Clear QC data provided on every lot from our ISO 9001:2015 accredited facility
    • Highly bioactive and potentially more bioactive than alternative suppliers
    • Long storage at -80 degree celcius for up to 2 years for most proteins
    • Multiple pack sizes to suit your research

R-Spondin 1

Featured product from Qkine


Human R-spondin 1 protein (RSPO1) is the prototypic member of the R-spondin family and is used to potentiate Wnt signalling in many organoid culture systems including intestinal and tumor (cancer) organoid culture. R-spondin 1 is also required for hematopoietic stem cell specification and cancer cell migration and survival.

13kDa highly pure, bioactive domain of human R-spondin 1 comprising the two cysteine-rich furin-like domains of R-spondin 1, which are necessary and sufficient for Wnt signalling potentiation and are the essential domains for activity in stem cell and organoid culture. Qk006 is animal-free and not glycosylated to ensure production of homogeneous protein and enhanced comparability between batches. Used to replace R-spondin conditioned media for improved reproducibility in chemically defined organoid culture media.


[WEB] Product specification: recombinant human R-spondin 1 protein (Qk006)

[Technote] R-Spondin 1 in pancreatic organoids

[WEB] Featured products from Qkine

[WEB] Product specification: recombinant human R-spondin 1 LR5 protein (Qk031)

Drop us a line today to learn more about our comprehensive recombinant protein selection.


  1. Qkine, ‘recombinant human R-spondin 1 protein (Qk006)’, Available at

All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use. 

Contact us to explore our recombinant protein offerings.

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