Flyer: Cancer immune checkpoint antibodies from Genetex

by | Apr 9, 2024 | Cancer, Immunology

FLYER ON CANCER IMMUNE CHECKPOINT

GENETEX: CANCER IMMUNE CHECKPOINT ANTIBODIES

Increasing knowledge of how cancer cells escape immune destruction has significantly driven the evolution of cancer immunotherapy. In particular, studies describing how different immune checkpoints, including the PD-1 and CTLA-4 pathways, function to attenuate T cell antitumor activity have revealed novel opportunities for therapeutic intervention. Researchers have made promising strides in inhibiting these checkpoints to unleash the T cells’ tumor-killing potential.

Given that both radiotherapy and chemotherapy can also mobilize antitumor T cells, there is great excitement that checkpoint inhibition and other immunomodulatory approaches can be combined with conventional modalities to maximize clinical outcomes for a number of malignancies.

All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.

ABOUT GENETEX

With a 27-year production history, GeneTex continues to distinguish itself by emphasizing reagent validation.

Founded by scientists for scientists, GeneTex understands that researchers expect and demand product fidelity.

With a 27-year production history, GeneTex distinguishes itself by emphasising reagent validation. Poorly characterized antibodies remain an industry-wide challenge that impacts progress in the life sciences and biomedicine.

At GeneTex, product reliability is their primary concern. Stringent protocols have been established to validate their antibodies for various applications, including WB, IP, IHC, ICC/IF, FACS, and ELISA, using cell lines with known target protein expression levels and a diverse array of tissue samples. Lot-to-lot antibody performance is maintained through a combination of fully characterized reference lots, clone verification, and thorough quality control.

GeneTex products are made to standards outlined in quality management systems ISO 9001:2015, ISO 13485:2016 and ISO 14001: 2015.

Featured antibodies

Featured GeneTex antibodies in cancer research, neuroscience research, infectious diseases research, immunology research, metabolism research, as well as zebrafish-validated antibodies, Drosophila-validated antibodies, cell markers etc.

All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.

Reference: 

  1. GeneTex, ‘Tumor markers’ Available at https://www.genetex.com/upload/media/MarketingMaterial/PDF/DM/genetex_Tumor-markers-brochure-300dpi.pdf

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