Protocol for the creation of branched pancreatic organoids from hiPSCs

by | Mar 12, 2025 | Organoids, Stem Cell, Virology

KEY PUBLICATIONS USING QKINE

PROTOCOL: CREATION OF BRANDED PANCREATIC ORGANOIDS FROM hiPSCs

Qkine highlighted a journal article of Darrigrand et al. from the King’s College London, about the protocol in creating branched pancreatic organoids from human induced pluripotent stem cells (hiPSCs) by optimizing organoid culture format and media using Qkine activin A, EGF, FGF-7 and FGF-10.

The pancreas has vital endocrine and exocrine functions that can be affected by life-threatening diseases such as diabetes and pancreatic cancer. While animal models have been useful for understanding pancreatic development and disease, they are limited by their low-throughput and physiological differences. Generating 3D in vitro models, organoids, that are physiologically relevant is important for investigating human pancreatic development and disease. It may also allow the partial replacement of animal models used to investigate diseases such as pancreatic cancer. 

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ABOUT QKINE

A UK Manufacturer Provides Cost-Effective Highly Bioactive Growth Factors For Stem Cell and Organoid Research

 

Qkine manufactures high-purity, animal-free growth factors, cytokines and other complex proteins for stem cell and organoid culture. An ISO 9001: 2015 certified company based in Cambridge, UK, Qkine combines proprietary production processes with protein engineering technology to tackle fundamental biological and scale-up challenges.

 

    • Highly bioactive 
    • Animal-free to eliminate the risks of contaminating growth factors, viruses, and prions
    • Manufactured in UK
    • Clear QC data provided on every lot from our ISO 9001:2015 accredited facility
    • Excellent lot-to-lot consistency to help increase the reproducibility of experiments
    • High purity
    • Long-term stability
    • Multiple pack sizes to suit your research

LAB-A-PORTER IS THE OFFICIAL DISTRIBUTOR OF QKINE IN HONG KONG

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