Find the key
signatures of cancer.

You seek more than patterns. You seek the sources of disease. That is why our Tapestri Platform analyzes genotype and phenotype simultaneously from the same single cells, letting you reveal clonal heterogeneity and target comprehensive biomarkers that help stratify patients more precisely, signal resistance as it begins, and predict relapse.

KEY BENEFITS

CASE STUDY

APPLICATIONS

WORKFLOW

RESOURCES

Why Single Cell for DNA and Protein?

Cancer is a complex disease with a mix of cells with varied states, and understanding of the disease state at the cellular level is required for better therapies. A single-cell multi-omics approach is the only way to achieve full resolution, revealing the complex interplay between genotype and phenotype. Perform true multi-omics with simultaneous detection of SNVs, CNVs, and protein at the single-cell level.

Correlate immunophenotype with genotype from the same cell.
Distinguish subclones from minimal residual disease with multiple analytes in the cell using SNVs, CNVs, and protein expression.
Eliminate inferences while saving on research budgets and analysis times.

Explore insights of single-cell multi-omics in myeloid malignancies.

Ross Levine, M.D., Memorial Sloan Kettering Cancer Center

Hematology

Clonal evolution impacts response, resistance, relapse, and residual disease

Solid Tumor

Profiling enables high resolution of the genomic diversity in a variety of tumor types

The Tapestri Workflow

Integrate seamlessly into your existing NGS workflow with sample prep and analysis solutions using the Tapestri single-cell sequencing platform

With our single-cell sequencing platform, use the Tapestri Instrument, reagents, and consumables up-front of your NGS system and then Tapestri Pipeline and Tapestri Insights software for data analysis and visualization.

Featured Resources

TECHNICAL NOTE

Correlations between genomic variants and protein expression in AML patient samples

LEARN MORE

VIDEO

What if?

LEARN MORE

SPOTLIGHT

Immune-Based Therapies for Hematology: Single-cell Multi-omics and Cell Therapies for Leukemias

LEARN MORE

CAPABILITIES

DNA Is Our Foundation

Providing cancer researchers with the only single-cell multi-omics solution that simultaneously detects SNV, CNV, and protein data from the same cell.

Single-cell Genomics (DNA)

SNV

Detect rare clonal populations and identify co-occurrence and zygosity.

LEARN MORE

SNV + CNV

Characterize genomic heterogeneity using a single, comprehensive platform.

LEARN MORE

Single-cell Multi-omics (DNA+)

DNA + Protein

Gain a true multi-omics picture from genotype to phenotype.

LEARN MORE

Ready to build your DNA + Protein panel?

Chat with one of our design experts to build a panel to simultaneously detect SNVs, CNVs, and protein expression.