FOCUS BIOMOLECULES
Based in the United States, Focus Biomolecules was founded by former members of globally recognized BIOMOL. They set out to refine the practices of small molecule based life sciences companies and eliminate the challenges often found by customers. With more than 40 years in the industry, they offer advanced, high quality reagents and a fresh, customer oriented experience.
ABOUT THE SUPPLIER
Provides comprehesive cellular signaling tools
Focus Biomolecules’ products represent a comprehensive portfolio of chemical tools designed to investigate a wide range of biological activities, from the molecular and cellular level to broader physiological and disease states. The offerings are divided into two main areas:
- Biochemical Targets
- Physiological Processes
Tools for research on biochemical targets
This category focuses on the specific molecules and molecular systems that the products act upon. It indicates a deep catalog for researchers studying the fundamental mechanisms of the cell. The key areas of focus include:
- Core Cellular Machinery: Products targeting essential cellular functions such as autophagy, the regulation of the cytoskeleton, processes of cellular trafficking, and the ubiquitin/proteasome system for protein degradation.
- Gene Expression and Epigenetics: A strong focus on the regulation of genes, including tools that affect epigenetic modifications, gene regulation itself, and the activity of transcription factors and nuclear receptors.
- Signal Transduction Pathways: A comprehensive selection of molecules that modulate cell signaling, including agents that target G-Protein Coupled Receptors (GPCRs), various ion channels, a wide array of kinases, and signaling molecules like bioactive lipids.
- Cellular Integrity and Metabolism: Reagents to study DNA damage and repair mechanisms, mitochondrial function, and overall cellular metabolism.
Tools for research on physiological processes
This category highlights the broader biological and medical contexts in which these biochemical tools can be applied. It shows a commitment to providing relevant reagents for preclinical and basic science research into various health and disease areas. The key applications include:
- Disease Research: A major focus on providing tools for the study of cancer, neurodegeneration, diabetes, and cardiovascular diseases. The portfolio also supports research in immunology, inflammation, pain, and obesity and metabolic diseases.
- Cellular and Developmental Biology: Products aimed at investigating fundamental processes such as angiogenesis (the formation of new blood vessels), the cell cycle, cellular senescence (aging), and responses to cellular stress. The offerings also cater to research in programmed cell death (apoptosis), stem cell biology, and the circadian clock.
FEATURED PRODUCTS
IntelliScreen™ Chemical Libraries – Libraries & Mini-Libraries
Curated collections of small molecules targeting specific pathways, such as kinase inhibitors or cancer metabolism modulators. These products can be used by researchers performing screening experiments.
Mini-Libraries
Intelliscreen™ Polycomb Repressive Complex Inhibitors Mini-Library
Intelliscreen™ Wnt/β-catenin (canonical) Mini-Library
Intelliscreen™ Protein Kinase C Mini-Library
Intelliscreen™ Neuropathic Pain Ion Channel Mini-Library
Intelliscreen™ Cholesterol Metabolites Mini-Library
Intelliscreen™ DNA Damage Inducers Mini-Library
Intelliscreen™ Immunoregulatory Kinase Inhibitor Mini-Library
*All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.