Recombinant FGF2-G3 protein
Why Qkine FGF2-G3?
Compare directly with your existing FGF-2
- For the first time, a 145 aa FGF-G3 (Qk052) is also available so you can compare directly with your existing FGF-2.
No His tag here!
- We don’t like His tags. They increase contaminants, introduce scientific uncertainty and lead to issues when scaling or translating discoveries.
High purity and animal-free
- All our proteins are animal-free with extensive biochemicla and bioactivity data for every lot. Manufactured in our ISO9001:2015 certified facility.
What is FGF2-G3 (FGF2-STAB®)?
FGF 2 is essential in stem cell media but ingerently unstable
- FGF 2 is prone to prone to proteolytic degradation and aggregation in solution and in media
- In culture, the half-life of FGF 2 is <10 hours, with reports as low as 40 minutes
- This contributes to the need for frequent media changes and creates challenges in improving homogeneity during stem cell proliferation and subsequent differentiation
FGF2-G3 is a hyperstable form of FGF 2 with the same bioactivity
- FGF2-G3 contains an optimal set of nine amino acid substitutions that stabilize FGF 2 without affecting FGF receptor binding
- Functional half-life in culture is increased to >20 days
Enables highly homogrneous iPSC and hESC culture
- Core ingredient in B8 weekend-free media
- Facilitates optimisation of protocols for homogeneous iPSC culture and efficient differentiation
Read more on Qkine recombinant FGF2-G3 protein
BrochureRecombinant FGF2-G3 protein
All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.
References:
- Qkine. “Recombinant FGF2-G3 protein” Retrieved 12 July 2022, from https://qkine.com/product/recombinant-fgf2-g3-protein-qk053/