Immunotherapy Articles

CAR T-Cell Immunotherapy

A 10-minute reading on the basics of CAR-T Cell Immunotherapy.IntroductionChimeric antigen receptor (CAR) T cells are engineered to express receptors that enable the targeting of specific proteins, namely those found on the surfaces of tumor cells. CAR T cells contain...

PeproTech Media Products

PeproTech’s line of PeproGrow™ Cell Culture Media, Media Supplements and Companion Products are aimed at supporting your culturing needs. With these products we strive to redefine the quality of culture media and media companion products while continuing to offer...

Anti-tumor T cell responses through LAG-3 blockade

Lymphocyte-activation gene 3 (LAG-3) is a receptor that negatively regulates the proliferation, activation, and effector function of T cells. Currently, monoclonal antibodies that block the interaction of LAG-3 with its canonical ligand, MHC-II, are being evaluated...

Targeting sphingolipid metabolism enhances cancer immunotherapy

CTLA-4 and PD-1 based immunotherapies have demonstrated significant clinical efficacy in melanoma patients, but many patients remain non-responsive and relapse is common. To try and improve the response rate, researchers are currently working to develop innovative...