Immunotherapy Articles

Role of Ln-γ2 and TGF-β1 in anti-PD-1 therapy

OverviewThe PD-1/PD-L1 immune checkpoint plays an important role in serving immune escape for tumor cells. Tumor cells can bypass antitumor immunity by manipulating these immune checkpoints. In a research article from Frontier, the authors commented that immunotherapy...

Blocking of Interleukin 7 (IL-7) signaling pathway reverses spot baldness

OverviewInterleukin-7 (IL-7) is a cytokine that has been known regarding its effects on T-cells and B-cells. Its signaling pathway has a crucial role in controlling T cell function and its survival. In the recent article published by Science Advances, the authors...

Anti-SARS-CoV-2 antibody inhibits variants of concern

OverviewbioRxiv has recently released a preprint discussing a compelling neutralizing anti-SARS-CoV-2 antibody that hinders variants of concern. The authors identified one monoclonal antibody (mAB), the SARS2-38, powerfully neutralizes all SARS-CoV-2 variants of...

Immunotherapy Awakens the Immune System to Fight Disease

Over the last few decades, there have been numerous advancements in cancer treatments and technologies. Historically, cancer has been treated through three modalities:Surgeryused to excise visible tumorsChemotherapyused to prevent the proliferation of tumors using...