ALLEGROW
Allegrow Biotech is a biotechnology company specialising in immunomodulation through biomimetic approaches, based in Hong Kong Science and Technology Park (HKSTP). They combine chemical and biological engineering, cell biology, and data science to develop research and clinical tools for immune cell therapy.
ABOUT THE SUPPLIER
Founded in March 2022, Allegrow Biotech is a biotech specialising in immunomodulation via biomimetic approaches, based in HKSTP. The company was established with a vision to decode complex cell surface signaling pathways, enabling the development of next-generation cell therapy products that prioritize both clinical quality and cost-effectiveness.
By integrating expertise across chemical/biological bioengineering, cell biology and data science, Allegrow has developed its proprietary AimGel™ artificial cell technology. This platform mimics the immunological synapse to activate and expand immune cells with higher cell expansion, better viability and reduced exhaustion. All products are developed and expanded at their state-of-the-art R&D base in Hong Kong, ensuring high-purity, ready-to-use solutions for the global research community.
Allegrow’s commitment to innovation has been recognized with prestigious accolades, including the Gold Medal at the 48th Geneva International Exhibition of Inventions and being named a Winner at Jumpstarter 2023.
PRODUCT TECHNOLOGY
AimGel™ Technology: Activating Immune Cells as Nature Intended
Allegrow’s proprietary AimGel™ platform redefines immune cell expansion by providing gentle, native-like activation that mimics the natural immunological synapse. By replacing rigid plastic beads with a biomimetic interface, researchers can achieve superior results with a more streamlined workflow.
Core Features & Research Advantages
Gentle, Native-Like Activation: AimGel™ technology provides a biomimetic interface that activates cells more naturally than traditional rigid methods.
Rapid Growth & Minimized Exhaustion: The platform is engineered for consistent performance, promoting rapid expansion while significantly reducing cell exhaustion.
Biomimetic Design: Results in higher cell expansion, better viability, and more effective yet gentler activation than rigid magnetic microplastic beads.
Self-Degrading Matrix: A self-degradable, hydrogel-based activation that naturally hydrolyzes and degrades, eliminating the interference of rigid plastic beads and labor-intensive “debeading”.
Defined, Consistent, Compliant: 100% synthetically derived with fully defined structures and ratios to ensure no batch-to-batch variability.
One Platform, Unlimited Applications: Degradation kinetics, bead size, and signal loading capacity are all chemically tuneable, giving you precise control over activation parameters.
The Platform Adapts to Your Research: Configure specific applications by adjusting activation duration or coordinating with lentiviral transduction timing.
PRODUCT PORTFOLIO
Allegrow Biotech’s product portfolio is divided into two main categories: their proprietary activation and expansion reagents (AimGel™ Technology) and their ready-to-use expanded immune cells.
PRODUCT HIGHLIGHTS
1. Ready-to-Use Expanded Immune Cells
Accelerate your research breakthroughs with high-purity, high-potency Expanded Human NK Cells and Expanded T Cells. Powered by Allegrow’s proprietary AimGel™ technology, these products are specifically engineered to meet the rigorous demands of Hong Kong’s leading research institutions.
- Research Applications: Supports drug screening, immunology, oncology, and autoimmune research
- Proprietary AimGel technology: Activated & expanded with AimGel technology for gentle, native-like stimulation
- Reliable: Rapid growth, minimized exhaustion, consistent performance
- Convenience: Ready-to-use consumables — skip isolation & culture steps
- Fast Delivery: Grown in their Hong Kong lab, shipped within 3 working days
- Affordable: Cost-effective without compromising quality
Expanded CD3+ pan T cells
- Expanded from human PBMC with AimTconv™, representing the entire T cell population, providing a broad platform for immunological studies.
- Ideal for exploring general T cell activation, signaling, and drug screening assays.
- Vial size: ≥4M
- Viability after recovery: ≥80%
- CD3+ fraction: ≥90%
Expanded CD4+ helper T cells
- Key regulators of the immune system, orchestrating cytokine release and immune coordination.
- Crucial for studying autoimmune disorders, infectious diseases, and vaccine responses.
- Vial size: ≥4M
- Viability after recovery: ≥80%
- CD4+ fraction: ≥75%
Expanded CD8+ cytotoxic T cells
- Specialized in directly killing infected or malignant cells.
- Widely used in oncology, antiviral research, and immunotherapy development. A powerful tool for modeling cell-mediated cytotoxicity in vitro.
- Vial size: ≥4M
- Viability after recovery: ≥80%
- CD8+ fraction: ≥90%
Expanded CD3-CD56+ NK cells
- Innate immune cells with rapid, non-MHC restricted cytotoxic activity.
- For research in tumor surveillance, viral infections, and immunotherapy approaches.
- Providing a unique lens into innate immunity and early defense mechanisms.
- Vial size: ≥4M
- Viability after recovery: ≥80%
- CD56+ CD3- fraction: ≥80%
- CD56+ CD16+fraction: ≥70%
2. Aim-Tconv | Human T Activator
AimGel™ for T cell activation and expansion. For Research Use Only.
Aim-Tconv is an efficient T cell activation and expansion system built on AimGelTM’s biomimetic lipid membrane and self-degrading hydrogel technology. Unlike traditional magnetic microplastic beads, Aim Tconv eliminates the need for bead removal procedures and works directly with PBMCs — streamlining your workflow from sample to expansion.
3. Aim-NK | Human NK Activator
AimGel for NK cell activation and expansion. For Research Use Only.
Aim-NK is a high-efficiency NK cell activation and expansion system built on AimGelTM’s biomimetic lipid membrane and self-degrading hydrogel technology. Unlike microplastic beads that require removal steps or coated well-plates that need preparation, Aim-NK is simple: just add to your culture and expand—no prep, no cleanup, no debeading. Aim-NK works directly with PBMCs, eliminating time-consuming cell isolation steps.
4. Aim-Core | Blank AimGel Artificial Cells
Blank AimGel artificial cells for custom signals. Research Use Only.
Aim-Core is the essence of Allegrow’s technology, AimGel artificial cells with a blank canvas for you to dock any signals onto the surface for cell-like presentation. All signals are welcome as long as they are biotinylated, and attach to the artificial cells via simple mixing. This makes Aim-Core perfect for investigating niche cell subtypes, workflows or even species, where generic labels like T cells or NK cells do not suffice. They offer a selection of Aim-Core beads to give users choices in persistence in the culture media (degradability), signal loading capacity (avidin amount) and membrane fluidity.
Aim-Core is the ultimate platform for users to explore cell-signalling interactions with unprecedented biomimicry while maintaining a simple mix-and-grow workflow.
5. Aim-Treg | Human regulatory T Cell Activator
Activator for human regulatory T cells. For Research Use Only.
All products listed on this site and sold through LAB-A-PORTER Limited are for research use only (RUO). Not for human use. Not for therapeutic or diagnostic use.