Stem Cell Articles

Differentiation of Embryonic and Induced Pluripotent Stem Cells

Pluripotent stem cells possess the capacity for indefinite self-renewal and the potential to differentiate into all adult cell types of the three primary germ layers. These features nominate pluripotent stem cells as a major component in the field of regenerative...

Chemical Transdifferentiation

Chapter 4: Chemical TransdifferentiationRegenerative medicine, which can replace lost or damaged cells in a variety of tissues and organs, requires sufficient amounts of the desired competent cells for transplantation. Such cells can be obtained by the reprogramming...

Chemically Induced Pluripotent Stem Cells (iPSCs)

Chapter 3: Chemically Induced Pluripotent Stem CellThe use of human embryonic stem cells (hESCs) in research and for therapeutic applications is a controversial issue due to a combination of religious, political and ethical considerations. This led researchers to...

Improving Reprogramming Efficiency

Chapter 2: Improving Reprogramming EfficiencyInduced pluripotent stem cells (iPSCs) hold several advantages over embryonic stem cells (ESCs), including avoiding the ethical issues involved with ESCs, the availability of an “endless” cells source and the ability to...