InVivoMAb anti-mouse NKG2D (CD314) (Clone: CX5)

Useful for in vivo and in vitroΒ  NKG2D blockade

The CX5 monoclonal antibody reacts with mouse NKG2D, a type II transmembrane lectin-like glycoprotein also known as CD314. NKG2D is expressed on NK cells, NKT cells, CD8 T cells, Ξ³/Ξ΄ T cells, and macrophages. NKG2D has been implicated in anti-tumor surveillance, the immune response against viral infection, and in diabetes progression in NOD mice. Previous studies have shown that CX5 is a non-depleting antibody, which blocks binding of NKG2D to its ligands and mediates internalization of the receptor.

This Antibody Is Useful For:

  • in vivoΒ NKG2D blockade
  • in vitroΒ NKG2D blockade
  • Flow Cytometry

As always Bio X Cell antibodies are specifically formulated forΒ in vivoΒ use and feature:

  • 95% purity
  • Ultra-low endotoxin levels
  • Preservative, stabilizer, and carrier protein-free

Don’tΒ forget to add the recommended isotype control antibody and dilution buffer.

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