Organoid models include three-dimensional (3D) cell culture systems that closely resemble in vivo organ or tissue. These 3D systems reproduce the complex spatial morphology of a differentiated tissue to allow biologically relevant cell-cell and cell-matrix interactions, ideally, sharing similar physiological responses with in vivo differentiated tissues.

The major focus of future organoid studies, beside the study of developmental processes, will most likely be in drug testing and disease modeling, such as developmental disorders, genetic conditions, cancer and degenerative disorders. The hope is that organoids are another step in the long way towards in vitro construction of tissues and organs for transplantation in patients.