Special Promotion

20% OFF on Small Molecules when bundling with PeproTech recombinant proteins

Promotion code: LAP1807  |  Valid until 31st Dec. 2018   

Small molecules are low molecule weight organic compounds that affect key biological pathways to allow for the control of cellular responses. Their small size allows them to diffuse rapidly across cell membranes to reach intracellular sites of action.

Unlike proteins or peptides, small molecules can be designed to be orally active and metabolically stable. Small Molecules are used in a variety of applications involving stem cells and organoids culture in developmental studies, disease modeling cellular therapy, and regenerative medicine.

PeproTech small molecules features the following advantages.

Function

Widely used for the generation, maintenance, and differentiation of stem cells.

Reproducibility

Minimize experimental variability with high purity chemically defined reagents.

Precision

Target specific steps within the signaling pathway.
Key Products:
Y-27632 Dihydrochloride
Y-27632 is a selective inhibitor of Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK) family of protein kinases that selectively competes with ATP for binding to the catalytic site. It is reported to diminish dissociation-induced apoptosis, increase cloning efficiency, and facilitate subcloning after gene transfer in human embryonic stem cells (hES).
CHIR 99021

CHIR 99021 is an aminopyrimidine derivate that is a selective and potent inhibitor of glycogen synthase kinase 3 (GSK-3). It is used to maintain human and mouse stem cell lines and, in combination with other reagents, to chemically reprogram somatic cells into stem cells.
SB 203580
SB 203580 is a p38 specific inhibitor that prevents the downstream activation of heat shock protein 27 and MAP kinase-activated protein kinase 2 (MAPKAPK2). It can have anti-proliferative activity on cytokine-activated lymphocytes and is reported to be used to enhance cardiomyocyte differentiation.

Explore full range of small molecules

Special Promotion

20% OFF on Small Molecules when bundling with PeproTech recombinant proteins

Promotion code: LAP1807  |  Valid until 31st Dec. 2018